
- Longevity
- Weight management
- Metabolic health
Dr. Benjamin H. Krasne, M.D.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
Zepbound is tirzepatide approved by the FDA in 2023 for chronic weight management. The SURMOUNT-1 trial demonstrated 20-22% average body weight loss at 72 weeks — substantially higher than any prior medication. Weekly injection, full clinician support.
Zepbound (tirzepatide) is the brand-name dual GIP/GLP-1 receptor agonist FDA-approved in 2023 for chronic weight management. The SURMOUNT-1 trial — the largest randomized weight loss trial in modern medicine — showed an average 20.9% body weight loss at the 15 mg dose at 72 weeks. SURMOUNT-2 confirmed similar effects in members with type 2 diabetes.
In 2024 the FDA approved Zepbound for an additional indication: obstructive sleep apnea (OSA) in adults with obesity. The SURMOUNT-OSA trial showed substantial reductions in apnea-hypopnea index and many members no longer requiring CPAP therapy after treatment. This was the first medication approval for OSA.
Zepbound contains the same active molecule as Mounjaro, just approved under a different label and dose schedule for weight management. HealifyNow prescribes Zepbound when appropriate and available; we also prescribe compounded tirzepatide from licensed U.S. compounding pharmacies as a more accessible alternative for members.
Primary FDA indication.
Same as Wegovy criteria.
New 2024 indication; many members reduce or eliminate CPAP need.
SURMOUNT-1 showed greater weight loss than any other approved medication.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
Same dual-agonist mechanism as Mounjaro. GLP-1 receptor activation produces appetite reduction, slowed gastric emptying, and glucose-dependent insulin response. GIP receptor activation adds enhanced insulin sensitivity, increased lipolysis, and additional weight-loss effects.
The dual mechanism produces a different and stronger clinical effect than GLP-1 alone. In head-to-head comparison, members on tirzepatide consistently lose more weight than members on semaglutide at comparable doses.
The sleep apnea benefit appears to come from a combination of weight loss (reducing pharyngeal soft tissue) and direct effects on upper airway function. Many members see improvement in apnea-hypopnea index even before reaching their full weight loss.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Slow titration essential. Most resolve within weeks.
MTC or MEN2 personal/family history rules out use.
Discontinue 2 months before conception.
Rapid weight loss increases gallstone risk.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
Single-dose pre-filled pens or vials, once weekly subcutaneous. Abdomen, thigh, or upper arm; rotate sites.
Titration: 2.5 mg for 4 weeks, then 5 mg. Increase by 2.5 mg every 4 weeks as needed for further weight loss and as tolerated, to maximum 15 mg. Many members are at goal by 10-12.5 mg.
Refrigerate; room temp up to 21 days. Visits every 4-12 weeks during titration; quarterly to biannually after stable.
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Patients served across the U.S.
Member satisfaction with care team
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We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.

A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.

A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.

A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Started Zepbound at 248 lbs, BMI 38. Twelve months later: 197 lbs, BMI 30. Knee pain gone, off two blood pressure meds. The food noise quieted within three weeks and that alone was life-changing."
"Tried every diet for 20 years. Zepbound is the first thing that actually worked. Down 41 lbs in 8 months. The hunger I'd been fighting since adolescence finally stopped."
"HealifyNow's process was simple. Labs, phone or video visit, prescription. Down 28 lbs in 5 months on Zepbound. Felt supported the entire way."
HealifyNow makes it easy to move forward with confidence. Here are the answers to what people ask us most.
Indirect comparisons and a recent head-to-head (SURMOUNT-5) show Zepbound produces greater weight loss than Wegovy — ~20% vs ~15% on average at similar timepoints.
Same molecule (tirzepatide). Zepbound is the weight management brand; Mounjaro is the diabetes brand.
The 2024 OSA indication has changed insurance coverage discussions. Medicare and many commercial plans are reviewing coverage updates; we help you check current status.
Combination of weight loss (reducing pharyngeal soft tissue) and direct upper airway effects. Many members reduce or eliminate CPAP need with treatment.
Appetite suppression often within the first week. Visible weight loss by week 4-6. Average 1-2 lbs/week of loss at therapeutic dose.
SURMOUNT-4 showed significant weight regain in members switched to placebo. Long-term use is the appropriate approach for chronic weight management.
Yes — HealifyNow prescribes compounded tirzepatide from licensed U.S. compounding pharmacies at substantially lower price than brand Zepbound. Same active molecule.
Decisively yes. Older weight loss drugs (fen-phen, sibutramine, lorcaserin) had serious safety issues. GLP-1/GIP class has a well-characterized safety profile with cardiovascular benefits.
Yes. Telehealth prescribing is legal when a licensed clinician evaluates you first. Zepbound is only prescribed when it's clinically appropriate, and it's filled by a licensed U.S. pharmacy.
Zepbound pricing is $399/month. Your first consultation is free, you don't need insurance, and your clinician confirms the exact cost before anything is prescribed.
Zepbound is typically prescribed for adults with a BMI of 30 or higher, or 27 or higher with a weight-related condition such as high blood pressure, type 2 diabetes or sleep apnea, and adults with obesity and moderate-to-severe obstructive sleep apnea. Your clinician reviews your health history, current medications and goals before deciding whether it's right for you.
No. Care is self-pay with flat, published pricing, so you don't need insurance, referrals or prior authorizations to get started.
Your clinician reviews your medical history, current medications, past treatments and goals by secure video or phone, explains the benefits and side effects, and agrees a plan with you. Labs may be ordered if needed.
Sometimes. Depending on your history, your clinician may ask for recent results or order a lab panel before prescribing Zepbound. Lab testing can be arranged at draw sites nationwide.
The most common side effects are nausea, diarrhea, constipation, vomiting and reduced appetite, usually strongest when starting or increasing the dose. Your clinician adjusts dosing and checks in to help you manage them.
Book a free consultation. Real evaluation, transparent pricing, clinical support.