Bupropion-naltrexone prescribed online — the oral weight-loss combination, done right
Bupropion-naltrexone (sold as Contrave) is an oral medication approved for chronic weight management. HealifyNow evaluates whether it fits your history and goals, prescribes when appropriate, and monitors you throughout.
What Bupropion-Naltrexone is
Bupropion-naltrexone combines two well-established medications. Bupropion is used for mood and smoking cessation, and naltrexone is used in addiction medicine. Together, at the doses used for weight management, they act on the brain pathways that influence appetite and cravings.
It is an option for adults with obesity, or who are overweight with a related health condition, when paired with diet and activity changes. Unlike GLP-1 injections, it is taken as a tablet — which some people prefer.
HealifyNow handles this through telehealth: a video visit with a licensed U.S. clinician, a thorough history review, a prescription sent to a licensed pharmacy when appropriate, and built-in follow-up to track progress and tolerance.
Eligibility
Qualifying indication
You meet the medical criteria for Bupropion-Naltrexone as evaluated by your clinician.
Pre-screening labs
Standard baseline labs are part of the program.
No contraindications
Personal and family medical history reviewed thoroughly.
Realistic expectations
Your clinician sets honest expectations about what the medication can and can't do.
How HealifyNow makes it simple
From your first message to your medication arriving at your door — clinician-guided, every step.
Schedule your free visit
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Meet your licensed clinician
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
Receive your prescription if appropriate
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
How it works
Bupropion-Naltrexone (oral semaglutide) works through the same mechanisms as the broader medication class. See our related pages for detailed mechanism discussion. Your clinician will explain how the medication relates specifically to your situation.
Important safety information
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Side effects review
Common side effects of Bupropion-Naltrexone are reviewed before and during treatment.
Drug interactions
Your clinician reviews all current medications.
Contraindications
Specific medical conditions or pregnancy may rule out use.
Ongoing monitoring
Periodic labs and visits during treatment.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
How to use Bupropion-Naltrexone
Your clinician provides detailed dosing instructions specific to your protocol. Standard practice includes a titration period (gradually increasing dose), regular follow-up visits, and lab monitoring at established intervals. We do not skip these steps.
Quick eligibility tool
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3 days
From visit to medication shipment
Why patients choose HealifyNow
We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
Easy Online Process
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
U.S.-Licensed Clinicians
Real physicians, nurse practitioners, and specialists licensed in your state. Not chatbots, not offshore call centers.
Discreet Home Delivery
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Support That Answers
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
The physicians behind your care
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.
Dr. Benjamin H. Krasne is a board-certified physician whose deep understanding of human physiology and clinical precision positions him as a powerful force in longevity and metabolic health. A graduate of the University of Miami Miller School of Medicine, Dr. Krasne completed his residency at Jackson Memorial Hospital — one of the nation's foremost academic medical centers — where he developed an advanced mastery of how the body responds to stress, recovery, and optimization at the physiological level.
Board-certified by the American Board of Anesthesiology, Dr. Krasne brings a uniquely rigorous, science-driven lens to longevity medicine and weight management. His expertise in pharmacology, pain physiology, and metabolic responses gives him a sophisticated foundation for understanding the biological mechanisms that drive aging, inflammation, hormonal imbalance, and weight gain — and, more importantly, how to reverse them.
Dr. Krasne believes sustainable weight loss and healthy aging are not the result of quick fixes, but of precise, personalized interventions rooted in clinical science.
Dr. Johnathan Chance Miller is a physician and holistic medicine practitioner dedicated to helping patients live longer, healthier, and more vibrant lives. Dr. Miller earned his medical degree from Columbia University College of Physicians and Surgeons in New York City and completed his internship and residency at Washington University in Saint Louis — institutions renowned for producing some of the country's most innovative medical minds.
A former collegiate athlete and rugby team captain, Dr. Miller understands firsthand the relationship between physical performance, nutrition, and long-term wellness. This lived experience drives his commitment to optimizing metabolic function, body composition, and healthspan for his patients.
As a physician at the forefront of holistic medicine, Dr. Miller blends cutting-edge science with personalized lifestyle strategies to address the root causes of weight gain, metabolic dysfunction, and accelerated aging.
Dr. Vanessa Niles is a board-certified Obstetrician-Gynecologist and Fellow of the American College of Obstetricians and Gynecologists (FACOG) with more than 40 years of experience in Obstetrics and Gynecology. She earned her Doctor of Medicine degree from Meharry Medical College and completed her residency training in Obstetrics and Gynecology at Brookdale University Hospital and Medical Center.
She has a well-established and respected history of worldwide medical collaboration, research, philanthropy, and outreach. She was appointed by former President Bush as an International Medical Ambassador, reflecting her global commitment to women's health and medical excellence.
Throughout her distinguished career, Dr. Niles has remained a passionate advocate for her patients, combining clinical expertise with a holistic, compassionate approach to care.
What members are saying
Real people, real results. Names and details published with permission.
"Started Bupropion-Naltrexone at 248 lbs, BMI 38. Twelve months later: 197 lbs, BMI 30. Knee pain gone, off two blood pressure meds. The food noise quieted within three weeks and that alone was life-changing."
"Tried every diet for 20 years. Bupropion-Naltrexone is the first thing that actually worked. Down 41 lbs in 8 months. The hunger I'd been fighting since adolescence finally stopped."
"HealifyNow's process was simple. Labs, video visit, prescription. Down 28 lbs in 5 months on Bupropion-Naltrexone. Felt supported the entire way."
Frequently asked questions
Is bupropion-naltrexone the same as Contrave?
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Contrave is the brand name for the fixed-dose combination of bupropion and naltrexone. The active ingredients are the same.
How is it different from semaglutide or tirzepatide?
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It is an oral tablet rather than an injection and works through different brain pathways. Average weight loss is generally more modest than with GLP-1 medications. Your clinician can help you compare options.
Who should not take it?
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It is not appropriate for people with uncontrolled high blood pressure, seizure disorders, certain eating disorders, or those using opioids, among other contraindications. Your clinician reviews your full history first.
How long until I see results?
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Appetite and craving changes can appear within the first weeks. Your clinician reassesses progress at follow-up and adjusts the plan as needed.
Get Bupropion-Naltrexone prescribed properly.
Book a free consultation. Real evaluation, transparent pricing, clinical support.