
- Longevity
- Weight management
- Metabolic health
Dr. Benjamin H. Krasne, M.D.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
Bupropion-naltrexone (sold as Contrave) is an oral medication approved for chronic weight management. HealifyNow evaluates whether it fits your history and goals, prescribes when appropriate, and monitors you throughout.
Bupropion-naltrexone combines two well-established medications. Bupropion is used for mood and smoking cessation, and naltrexone is used in addiction medicine. Together, at the doses used for weight management, they act on the brain pathways that influence appetite and cravings.
It is an option for adults with obesity, or who are overweight with a related health condition, when paired with diet and activity changes. Unlike GLP-1 injections, it is taken as a tablet — which some people prefer.
HealifyNow handles this through telehealth: a phone or video visit with a licensed U.S. clinician, a thorough history review, a prescription sent to a licensed pharmacy when appropriate, and built-in follow-up to track progress and tolerance.
You meet the medical criteria for Bupropion-Naltrexone as evaluated by your clinician.
Standard baseline labs are part of the program.
Personal and family medical history reviewed thoroughly.
Your clinician sets honest expectations about what the medication can and can't do.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
This combination works on the brain's appetite and reward systems rather than on GLP-1 receptors. Bupropion activates appetite-regulating neurons in the hypothalamus that reduce hunger.
Naltrexone blocks an opioid feedback loop that would otherwise dampen that effect, and it may also reduce reward-driven eating and cravings. Together they help you feel satisfied with less food.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Bupropion is an antidepressant. Watch for new or worsening depression, anxiety or thoughts of self-harm, especially early on, and tell your clinician right away.
Not for people with seizure disorders or eating disorders like bulimia or anorexia. Avoid heavy alcohol use and high-fat meals with doses.
Naltrexone blocks opioids. Don't take it with opioid pain medicines or opioid treatment, and tell every provider that you use it.
It can raise blood pressure and heart rate, so these are checked before and during treatment.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
The dose builds up over about four weeks until you reach two tablets twice a day. Swallow tablets whole and don't take them with a high-fat meal.
Your clinician checks your progress at about 12 weeks. If weight loss is limited at that point, stopping is usually recommended.
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We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.

A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.

A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.

A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Started Bupropion-Naltrexone at 248 lbs, BMI 38. Twelve months later: 197 lbs, BMI 30. Knee pain gone, off two blood pressure meds. The food noise quieted within three weeks and that alone was life-changing."
"Tried every diet for 20 years. Bupropion-Naltrexone is the first thing that actually worked. Down 41 lbs in 8 months. The hunger I'd been fighting since adolescence finally stopped."
"HealifyNow's process was simple. Labs, phone or video visit, prescription. Down 28 lbs in 5 months on Bupropion-Naltrexone. Felt supported the entire way."
Contrave is the brand name for the fixed-dose combination of bupropion and naltrexone. The active ingredients are the same.
It is an oral tablet rather than an injection and works through different brain pathways. Average weight loss is generally more modest than with GLP-1 medications. Your clinician can help you compare options.
It is not appropriate for people with uncontrolled high blood pressure, seizure disorders, certain eating disorders, or those using opioids, among other contraindications. Your clinician reviews your full history first.
Appetite and craving changes can appear within the first weeks. Your clinician reassesses progress at follow-up and adjusts the plan as needed.
Book a free consultation, answer a short health questionnaire, then meet a licensed clinician by secure video or phone. If bupropion-naltrexone is medically appropriate, your clinician sends the prescription to a licensed U.S. pharmacy and it ships to your door.
Yes. Telehealth prescribing is legal when a licensed clinician evaluates you first. Bupropion-naltrexone is only prescribed when it's clinically appropriate, and it's filled by a licensed U.S. pharmacy.
Bupropion-naltrexone pricing is from $129/month. Your first consultation is free, you don't need insurance, and your clinician confirms the exact cost before anything is prescribed.
No. Care is self-pay with flat, published pricing, so you don't need insurance, referrals or prior authorizations to get started.
Many members meet a clinician within a few days of booking. If bupropion-naltrexone is prescribed, it ships in discreet packaging and most orders arrive within 2 to 5 business days.
Your clinician reviews your medical history, current medications, past treatments and goals by secure video or phone, explains the benefits and side effects, and agrees a plan with you. Labs may be ordered if needed.
Sometimes. Depending on your history, your clinician may ask for recent results or order a lab panel before prescribing bupropion-naltrexone. Lab testing can be arranged at draw sites nationwide.
Yes. Visits take place on a HIPAA-compliant platform, your records are protected, and medication ships in plain, discreet packaging.
Yes. There are no contracts, and you can cancel from your patient portal. Medication that has already been dispensed can't be refunded.
Your clinician will tell you honestly and won't prescribe bupropion-naltrexone. They'll explain other options, which may include a different medication, lifestyle support or a referral.
Telehealth care is available in all 50 states,.
Book a free consultation. Real evaluation, transparent pricing, clinical support.