
- Longevity
- Weight management
- Metabolic health
Dr. Benjamin H. Krasne, M.D.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
Lipotropic injections combine methionine, inositol, choline (the 'MIC' base) with vitamin B12 and sometimes other B vitamins. They support liver fat metabolism, the methylation cycle, and energy — often added to weight loss programs to help members feel better while losing weight.
MIC injections have been used in weight loss medicine for decades. The science is real but more modest than some clinics imply.
The classic MIC injection contains three lipotropic compounds — methionine, inositol, and choline — plus vitamin B12. Some formulations add other B vitamins (B6, B5, B1). "Lipotropic" means literally "fat-loving" — these compounds support the liver's processing of fats and the methylation reactions that fat metabolism requires.
What lipotropic injections do well: support the methylation cycle (which is the foundation for fat metabolism, neurotransmitter production, DNA repair, and dozens of other things), provide injectable B12 (more bioavailable than oral, particularly useful during caloric restriction), and supply choline (a nutrient most Americans don't get enough of from food).
What lipotropic injections don't do: cause significant weight loss on their own. The "fat-burning shot" marketing common in some clinics oversells the effect. The realistic role of MIC injections is as a supportive therapy during a real weight loss protocol — typically alongside GLP-1 medication, caloric restriction, or both. They help members feel better during weight loss, which improves adherence, which is the actual driver of results.
Adjunct to GLP-1 medications, caloric restriction, or other weight protocols.
Many members feel run-down during active loss. Lipotropic injections help energy and motivation.
MTHFR variant carriers and members with elevated homocysteine often benefit from supplemental methyl donors.
Choline is mostly in animal foods. Vegetarian/vegan members are often choline-insufficient.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
Methionine. An essential amino acid and the source of the body's most important methyl donor (S-adenosylmethionine, or SAM-e). Supports methylation, antioxidant defense (via glutathione synthesis), and fat metabolism. Often deficient in caloric restriction.
Inositol. A B-vitamin-like compound involved in insulin signaling, neurotransmitter function, and ovarian function (relevant for women with PCOS). Has independent evidence for benefits in PCOS, anxiety, and insulin resistance.
Choline. An essential nutrient most Americans don't get enough of. Required for fat metabolism (chronic deficiency causes fatty liver), brain function (acetylcholine production), and methylation. Liver and eggs are the best dietary sources.
Vitamin B12. Methylcobalamin or hydroxocobalamin. Essential for the methylation cycle alongside methionine. Injectable B12 has 100% bioavailability versus 1-2% for oral.
When combined, these compounds support the same biochemical machinery — methylation, fat processing, energy production. Weekly injections produce sustained tissue levels and most members notice subjective effects within 2-3 weeks: better energy, clearer thinking, often improved skin and hair.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Lipotropic injections have an excellent safety record across decades of clinical use.
Some members get minor redness or tenderness at injection sites. Rotation prevents accumulation.
Very rare allergy to cobalt in B12 component. Tell your clinician if you have known cobalt sensitivity.
Lipotropic injections support weight loss; they do not cause it. Be wary of clinics advertising them as standalone fat-burning shots.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
Typical protocol: 1 mL injection given once or twice weekly, intramuscularly into the deltoid, gluteus, or thigh, or subcutaneously into the abdomen. Self-administration is easy after one training visit.
Most members start with weekly injections and assess response over 4-6 weeks. Some increase to twice weekly if results are favorable. The injections can be continued long-term safely; many members keep them as part of their ongoing protocol.
Combined with GLP-1 weight loss medication, lipotropic injections often help members navigate the energy and methylation demands of rapid weight loss. The combination is common in our weight loss programs.
Standalone for energy and methylation support — without weight loss intent — is also reasonable for many members, particularly vegetarians, those with MTHFR variants, or members feeling run-down.
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We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.

A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.

A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.

A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Started Wegovy and added weekly MIC. Energy through the calorie deficit was night-and-day better than my friend doing Wegovy alone. Down 28 lbs in five months, still functional at work and home."
"MTHFR carrier with chronic methylation issues. Weekly MIC plus separate methylfolate. Brain fog of 10 years finally lifted within six weeks. The combination clicked."
"Vegan for 12 years and feeling slowly worse. Choline and B12 were both low. MIC injections weekly transformed my energy in three weeks. Surprised it took me this long to figure out."
HealifyNow makes it easy to move forward with confidence. Here are the answers to what people ask us most.
No. They support a weight loss protocol; they don't drive significant loss by themselves. Most members combine them with GLP-1 medication or a real caloric protocol.
Lipotropic injections include B12 plus methionine, inositol, and choline. The MIC compounds add methylation support and choline supplementation that B12 alone doesn't provide.
Yes — most members self-inject after a brief training call by phone or video. The technique is similar to other subcutaneous or intramuscular injections.
Yes. Methionine is in meat, fish, and eggs; choline is concentrated in eggs and liver; inositol is in fruits, beans, and grains; B12 is in animal foods. Many members get insufficient amounts from diet alone, particularly choline.
Once or twice weekly is standard. The injections can be continued long-term safely.
Lipotropic compounds don't have significant interactions with most prescription medications. Your clinician will review your full list.
No. Lipotropic injections support systemic metabolism. Fat-dissolving injections (deoxycholic acid) are cosmetic injections into specific body areas to reduce localized fat. Completely different.
Most members notice energy and mental clarity changes within 2-3 weeks. The effect builds over the first 6-8 weeks.
Book a free consultation, answer a short health questionnaire, then meet a licensed clinician by secure video or phone. If lipotropic injections is medically appropriate, your clinician sends the prescription to a licensed U.S. pharmacy and it ships to your door.
Yes. Telehealth prescribing is legal when a licensed clinician evaluates you first. Lipotropic injections is only prescribed when it's clinically appropriate, and it's filled by a licensed U.S. pharmacy.
Lipotropic injections pricing is from $69/month. Your first consultation is free, you don't need insurance, and your clinician confirms the exact cost before anything is prescribed.
Lipotropic injections is typically prescribed for adults using them alongside a nutrition and activity plan; lipotropic blends are compounded and support, rather than replace, weight loss treatment. Your clinician reviews your health history, current medications and goals before deciding whether it's right for you.
No. Care is self-pay with flat, published pricing, so you don't need insurance, referrals or prior authorizations to get started.
Your clinician reviews your medical history, current medications, past treatments and goals by secure video or phone, explains the benefits and side effects, and agrees a plan with you. Labs may be ordered if needed.
Sometimes. Depending on your history, your clinician may ask for recent results or order a lab panel before prescribing lipotropic injections. Lab testing can be arranged at draw sites nationwide.
Book a free consultation to see if lipotropic injections fit your program. Honest about what they do and don't do.