
- Longevity
- Weight management
- Metabolic health
Dr. Benjamin H. Krasne, M.D.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
Mounjaro is the brand name for tirzepatide approved for type 2 diabetes. Unlike Ozempic, tirzepatide activates two incretin pathways — GIP and GLP-1. The result is the most effective glucose control and weight loss in modern diabetes medicine.
Mounjaro (tirzepatide) received FDA approval in 2022 for type 2 diabetes. It's the first dual GIP/GLP-1 receptor agonist in the US market. The SURPASS trial program demonstrated superior HbA1c reduction (~2.0-2.5%) and superior weight loss (~15-20%) compared to semaglutide head-to-head.
Tirzepatide activates two incretin pathways. GLP-1 receptor activation is the same mechanism semaglutide uses. GIP (glucose-dependent insulinotropic polypeptide) receptor activation adds a different and complementary effect — enhanced insulin sensitivity, increased lipolysis, and additional weight loss effects.
The same active molecule is approved as Zepbound for chronic weight management. Mounjaro is approved for type 2 diabetes; Zepbound is approved for weight loss. Same molecule, different FDA labels.
HbA1c above target on current therapy.
Or on metformin plus another agent without reaching HbA1c goal.
Mounjaro's weight loss effect is substantially stronger than older diabetes medications.
Head-to-head trials suggest tirzepatide produces greater glucose and weight effects than semaglutide.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
GLP-1 receptor activation. Same mechanism as semaglutide — slowed gastric emptying, appetite suppression, glucose-dependent insulin release, glucagon suppression.
GIP receptor activation. Distinct from GLP-1. GIP activation enhances insulin sensitivity, increases lipolysis (fat breakdown), and appears to add weight-loss effect beyond GLP-1 alone.
Net clinical effect. In SURPASS-2 head-to-head trial, tirzepatide 5/10/15 mg produced greater HbA1c reductions and greater weight loss than semaglutide 1 mg at 40 weeks. The 15 mg dose averaged ~12% body weight loss in diabetic patients.
Cardiovascular outcome data is still maturing. The SURPASS-CVOT trial is ongoing; SURMOUNT trials have shown favorable cardiovascular markers.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Slightly higher rates than semaglutide. Slow titration is key.
Same warning as semaglutide — personal or family history of medullary thyroid carcinoma rules out use.
Approved only for type 2.
Contraindication.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
Mounjaro is dispensed as single-dose pre-filled pens or vials. Once weekly subcutaneous injection.
Titration: 2.5 mg for 4 weeks, then 5 mg. Increase by 2.5 mg every 4 weeks based on glucose control and tolerance, to maximum 15 mg weekly. Most members do well at 7.5-12.5 mg for diabetes management.
Refrigerate; can be at room temperature 21 days once in use. Inject into abdomen, thigh, or upper arm; rotate sites.
HbA1c at 3 months. Lipid panel and weight at each visit.
Get a fast read on whether this is worth a deeper conversation.
Patients served across the U.S.
Member satisfaction with care team
Average review rating
From visit to medication shipment
We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.

A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.

A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.

A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Started Mounjaro at 248 lbs, BMI 38. Twelve months later: 197 lbs, BMI 30. Knee pain gone, off two blood pressure meds. The food noise quieted within three weeks and that alone was life-changing."
"Tried every diet for 20 years. Mounjaro is the first thing that actually worked. Down 41 lbs in 8 months. The hunger I'd been fighting since adolescence finally stopped."
"HealifyNow's process was simple. Labs, phone or video visit, prescription. Down 28 lbs in 5 months on Mounjaro. Felt supported the entire way."
HealifyNow makes it easy to move forward with confidence. Here are the answers to what people ask us most.
Head-to-head SURPASS-2 trial showed Mounjaro produced greater HbA1c reduction and greater weight loss than Ozempic 1 mg. Side effect profiles are similar.
Same active ingredient (tirzepatide). Mounjaro for diabetes; Zepbound for weight management.
Most commercial insurance covers Mounjaro for type 2 diabetes with prior auth. Coverage for off-label weight loss is uncommon.
The gradual titration (2.5 → 5 → 7.5 → 10 → 12.5 → 15) allows precise adjustment for response and side effect management.
Glucose effects within days. Significant HbA1c reduction at 12 weeks. Weight effects continue for 6-12+ months.
Generally similar profile. Some studies suggest slightly higher GI rates with Mounjaro at top doses; tolerable for most members with slow titration.
Mounjaro is FDA-approved for type 2 diabetes. Zepbound (same molecule) is appropriate for weight management with prediabetes considerations.
Long-term for diabetes management. Discontinuation typically results in glucose deterioration and weight regain.
Book a free consultation, answer a short health questionnaire, then meet a licensed clinician by secure video or phone. If Mounjaro is medically appropriate, your clinician sends the prescription to a licensed U.S. pharmacy and it ships to your door.
Yes. Telehealth prescribing is legal when a licensed clinician evaluates you first. Mounjaro is only prescribed when it's clinically appropriate, and it's filled by a licensed U.S. pharmacy.
Mounjaro pricing is $399/month. Your first consultation is free, you don't need insurance, and your clinician confirms the exact cost before anything is prescribed.
Mounjaro is FDA-approved for adults with type 2 diabetes; it isn't FDA-approved for weight loss alone, so if weight is your main goal your clinician may recommend an approved option such as Zepbound instead. Your clinician reviews your health history, current medications and goals before deciding whether it's right for you.
Your clinician reviews your medical history, current medications, past treatments and goals by secure video or phone, explains the benefits and side effects, and agrees a plan with you. Labs may be ordered if needed.
Sometimes. Depending on your history, your clinician may ask for recent results or order a lab panel before prescribing Mounjaro. Lab testing can be arranged at draw sites nationwide.
GLP-1 medications aren't recommended if you or a family member has had medullary thyroid cancer or MEN2, or if you're pregnant or planning a pregnancy. A history of pancreatitis also needs careful review. Your clinician screens for these first.
Book a free consultation. Comprehensive evaluation, transparent pricing, clinical follow-through.