
- Longevity
- Weight management
- Metabolic health
Dr. Benjamin H. Krasne, M.D.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
If injectable NAD+ feels like more commitment than you want, nasal spray is the easier on-ramp. Two sprays a day, absorbed through nasal mucosa directly into systemic circulation, no needles, no clinics.
Nasal absorption of small molecules is well-established — it is how nicotine, insulin, oxytocin, and several psychiatric medications are delivered.
The nasal mucosa is a thin, well-vascularized barrier that allows small molecules to enter systemic circulation rapidly, bypassing the digestive tract entirely. This matters for NAD+ because oral NAD+ is mostly degraded before absorption. Intranasal NAD+ provides a middle ground between oral precursors (NMN, NR) and the more committed injection route.
The dose delivered per spray is lower than an injection, which makes nasal spray better suited for daily maintenance use than acute high-dose therapy. Many members layer nasal NAD+ daily alongside less frequent injections, or use the spray alone as a starter approach. Either is reasonable.
Pharmaceutical-grade nasal NAD+ is compounded by licensed U.S. pharmacies. Quality matters — the same heavy metal contamination concerns that apply to industrial methylene blue apply to research-grade NAD+ sold without proper certification. HealifyNow only works with compounding pharmacies that provide certificates of analysis.
Easiest entry point. Lower commitment, lower cost, no needles.
Many members on weekly injections layer nasal NAD+ daily for steadier levels.
Compact, no syringes, no refrigeration concerns — easier to bring on the road.
A reasonable way to test NAD+ response before committing to injectables.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
NAD+ molecules absorbed through nasal mucosa enter systemic circulation rapidly and reach tissues throughout the body. There is also some evidence of direct nose-to-brain transport for small molecules, which is part of the rationale for nasal delivery of oxytocin, ketamine, and other CNS-relevant compounds. Whether this matters meaningfully for NAD+ is an open research question, but the mechanism is plausible.
Once absorbed, NAD+ participates in the same cellular processes as NAD+ from any other source: it fuels mitochondrial energy production, enables sirtuin activity, supports DNA repair, and supplies redox reactions. The mechanism downstream of absorption is identical to injectable NAD+.
The dose per spray is calibrated to be useful for daily maintenance — enough to keep NAD+ levels supported without the spike-and-trough pattern of less frequent dosing.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Most members feel nothing beyond mild nasal sensation immediately after a spray. Occasional sneezing or temporary stuffiness.
Only pharmaceutical-grade NAD+ from a licensed U.S. compounding pharmacy. Research-grade and industrial supplies are not appropriate.
NAD+ has no major prescription drug interactions, but your clinician will still review your full list.
If you have active sinus infection or significant nasal congestion, hold the spray until it clears.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
Standard dosing is 1-2 sprays per nostril, once or twice daily. Most members use it as part of their morning routine; some add a second dose mid-afternoon. There is no need to take it on an empty stomach or at any specific time relative to food.
Prime the bottle before first use as described in the included instructions. Tilt your head slightly forward, spray, and inhale gently. Avoid blowing your nose for several minutes after dosing.
Most members notice subjective effects within 2-4 weeks of consistent daily use — typically improved morning energy, sharper mental clarity, and better recovery from physical or cognitive load. Some notice nothing for the first couple of weeks; consistency matters more than dose.
Get a fast read on whether this is worth a deeper conversation.
Patients served across the U.S.
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We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.

A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.

A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.

A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Easier than I expected. I take it with my morning supplements. The energy effect snuck up on me — felt it strongly after about three weeks."
"Tried oral NMN for a year with no clear effect. Switched to nasal NAD+. Different experience entirely — I actually feel it. My partner noticed too."
"Use it daily, add an injection once a week. Best protocol I've landed on. Recovery and morning energy are both better than they've been in years."
HealifyNow makes it easy to move forward with confidence. Here are the answers to what people ask us most.
The dose per spray is lower, so peak levels are lower. For daily maintenance and most member goals, this is fine and often preferred. For aggressive high-dose protocols, injection delivers more NAD+ per dose. Many members use both: daily spray plus weekly injection.
Typical 30 mL bottles last roughly 30-60 days at standard dosing, depending on whether you use it once or twice daily.
Absorption is reduced when nasal mucosa is inflamed or blocked. Use during clear-nose periods, or pause until symptoms resolve.
Pharmaceutical NAD+ spray is typically stored at room temperature once opened, with a 60-90 day shelf life after first use. Refrigeration extends shelf life. Your pharmacy will include specific storage guidance.
Yes. NAD+ does not have the serotonergic interactions that methylene blue has. Your clinician will still review your medication list.
Some members find evening doses energizing and prefer to dose earlier in the day. Others are unaffected by timing. Easy to find what works for you.
Two to four weeks of consistent daily use is the typical window. A small minority notice acute effects within a few days; some take longer than four weeks.
Most members travel with their nasal spray without issue. Bring the prescription label and your clinician note. Some countries have stricter controls on imported compounded medications — check before international travel.
Book a free consultation, answer a short health questionnaire, then meet a licensed clinician by secure video or phone. If NAD+ nasal spray is medically appropriate, your clinician sends the prescription to a licensed U.S. pharmacy and it ships to your door.
Yes. Telehealth prescribing is legal when a licensed clinician evaluates you first. NAD+ nasal spray is only prescribed when it's clinically appropriate, and it's filled by a licensed U.S. pharmacy.
NAD+ nasal spray pricing is $199/month. Your first consultation is free, you don't need insurance, and your clinician confirms the exact cost before anything is prescribed.
NAD+ nasal spray is typically prescribed for adults looking for energy and cellular-health support; NAD+ is compounded and not FDA-approved to treat any condition, and human evidence is still emerging. Your clinician reviews your health history, current medications and goals before deciding whether it's right for you.
No. Care is self-pay with flat, published pricing, so you don't need insurance, referrals or prior authorizations to get started.
Many members meet a clinician within a few days of booking. If NAD+ nasal spray is prescribed, it ships in discreet packaging and most orders arrive within 2 to 5 business days.
Your clinician reviews your medical history, current medications, past treatments and goals by secure video or phone, explains the benefits and side effects, and agrees a plan with you. Labs may be ordered if needed.
Book a free consultation to see if daily nasal NAD+ fits your routine and goals.