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Mobile IV therapyThe Galleri test by GRAIL is a blood draw that screens for signals of 50+ cancer types, including many for which no standard screening exists. Coordinated through HealifyNow with real clinical context. Not a replacement for standard screening — an addition.
Most cancer screening today covers four cancers: breast, cervical, colorectal, lung (for high-risk smokers). MCED tests aim to broaden the screening footprint.
The Galleri test by GRAIL is a multi-cancer early detection (MCED) blood test. It analyzes patterns of DNA methylation in cell-free DNA circulating in the bloodstream. Cancer cells shed DNA with characteristic methylation patterns; the test uses machine learning to detect these signals and predict the tissue of origin when a positive result occurs.
The test screens for signals of more than 50 cancer types, including many for which no standard screening currently exists — pancreatic, ovarian, esophageal, gastric, and others. For these cancers, late-stage diagnosis is common because the disease is often asymptomatic until advanced. MCED testing is an attempt to shift detection earlier.
Important nuance: Galleri is not FDA-approved. It's available as a laboratory-developed test (LDT) through the GRAIL pipeline. Sensitivity varies by cancer type and stage — higher for some cancers, lower for others, and substantially higher at later stages than at early stages. The test is intended to complement, not replace, standard screening like mammograms, colonoscopies, and Pap smears.
A positive Galleri result is not a cancer diagnosis. It's a signal that warrants further workup, typically with imaging directed at the predicted tissue of origin. A negative result is reassuring but not definitive — some cancers will be missed. HealifyNow provides the clinical context: helping you understand whether the test is appropriate for you, what a result actually means, and what the next steps look like in either direction.
Age-related cancer risk rises substantially in this range. The largest evidence base supports MCED screening in this group.
Multiple first-degree relatives with cancer, particularly cancers without standard screening (pancreas, ovary, lymphoma).
MCED is a complement, not a substitute. Mammogram, colonoscopy, Pap, lung CT (for high-risk smokers) come first.
MCED tests have false positives and false negatives. Members need to understand and accept the limitations.
From your first message to your medication arriving at your door — clinician-guided, every step.
A care team member meets with you to understand your goals, medical history, and treatment preferences. The first visit is no-cost and no-commitment — we want you to be confident before moving forward.
Connect by secure video or phone with a U.S.-licensed physician or nurse practitioner who reviews your full picture — labs, prior treatments, current medications, and lifestyle — and decides what is clinically appropriate.
If your clinician determines treatment is right for you, they issue a prescription that goes to a licensed U.S. pharmacy. We coordinate discreet shipping, or you can fill it locally. Follow-up visits are built in.
Cell-free DNA. When cells die anywhere in the body (normal turnover, immune activity, or disease), small DNA fragments enter the bloodstream. Cancer cells shed DNA at higher rates and with characteristic methylation patterns.
Methylation analysis. The Galleri test sequences cell-free DNA and analyzes methylation patterns at specific genomic sites. Cancer methylation signatures differ from normal tissue methylation in characteristic ways.
Machine learning classification. Algorithms trained on tens of thousands of samples with known cancer status classify the methylation pattern as cancer signal detected or not. If detected, additional algorithms predict the cancer signal origin (tissue type).
Sensitivity and specificity. Galleri's overall sensitivity is moderate — roughly 50% across all stages and cancer types. Sensitivity is higher for later-stage and certain cancer types, lower for early-stage and certain other cancer types. Specificity is high (>99%) — meaning false positives are rare.
Follow-up imaging. A positive result is followed by directed imaging (CT, MRI, PET) based on the predicted tissue of origin. Most positive results are followed up within 4-8 weeks. A workup may confirm a cancer (allowing earlier intervention) or may identify a non-cancer cause of the signal.
Your clinician will review every relevant detail with you. Here are the most important points to know up front.
Galleri is a laboratory-developed test, not an FDA-approved diagnostic. The FDA has been reviewing the MCED category.
MCED tests don't replace mammogram, colonoscopy, Pap, or lung CT in eligible patients. Continue your standard screenings.
Approximately 0.5% false positive rate. Workup of a false positive can be anxiety-provoking and may include imaging not otherwise indicated.
A negative Galleri does not rule out cancer. Continue all standard screenings. New symptoms warrant evaluation regardless of MCED result.
All medications must be prescribed by a licensed provider based on medical necessity. Treatment is not suitable for everyone. Results may vary.
5–10 minute phone or video visit with a clinician to discuss your situation, family history, current standard screening status, and whether MCED testing makes sense for you. We're honest if we don't think it's appropriate.
If we proceed, we order the Galleri test through GRAIL's pipeline. You schedule a single blood draw at a participating phlebotomy site.
Results typically return in 10-14 business days. Two possibilities: "no cancer signal detected" (the large majority of results) or "cancer signal detected" with a prediction of cancer signal origin.
Negative result: continue standard screening, discuss whether to repeat MCED annually. Positive result: coordinated follow-up with directed imaging through your healthcare system. We support this transition.
MCED is intended as an annual screening tool, similar to other annual checks. Insurance generally doesn't cover Galleri — pricing is transparent.
Patients served across the U.S.
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From visit to medication shipment
We built HealifyNow because telehealth done badly is everywhere — and telehealth done right still feels rare. Here is what makes us different.
No waiting rooms, no faxed forms, no insurance hoops. Quick consults, simple intake, prescriptions handled digitally.
Real physicians, nurse practitioners, and specialists with active licenses. Not chatbots, not offshore call centers.
Medications ship from licensed U.S. pharmacies in plain packaging. Most orders arrive in 2-5 business days.
Reach a real human seven days a week. Most messages get a clinical reply within a few hours, not days.
HealifyNow prescriptions are reviewed and authorized by independently licensed physicians — real doctors with real credentials from top medical institutions in the United States.
A board-certified physician who brings a rigorous, pharmacology-driven lens to longevity medicine and weight management.
A Columbia-trained physician and former collegiate athlete focused on metabolic function, body composition, and healthspan.
A board-certified OB-GYN and ACOG Fellow with more than four decades of experience in women's health.
Real people, real results. Names and details published with permission.
"Father died of pancreatic cancer at 62. No standard screening for that. Galleri test gives me a degree of vigilance that simply didn't exist before. Negative results year over year are meaningful."
"Test came back positive with a predicted GI origin. Coordinated workup found early-stage colon cancer that was treatable. Standard colonoscopy was scheduled for 6 months later — too late for the type of treatment we did."
"Negative result was reassuring but my clinician was clear about the limitations. Continued my mammogram and colonoscopy schedule. The MCED is one piece, not the whole picture."
HealifyNow makes it easy to move forward with confidence. Here are the answers to what people ask us most.
No. Galleri is a laboratory-developed test (LDT) available through GRAIL. The FDA has been reviewing the MCED category but has not approved Galleri specifically. This affects insurance coverage and how we discuss the test with you.
No. Galleri screens for signals of more than 50 cancer types, but sensitivity varies by cancer type and stage. Overall sensitivity is roughly 50% across all stages and cancers. A negative result does not rule out cancer.
Generally no. Galleri is cash-pay through GRAIL's pipeline. Pricing varies — your clinician will discuss current pricing during the consultation.
No. Colonoscopy is the gold standard for colorectal cancer screening, with both detection and prevention (polyp removal) benefits. MCED tests don't replace it. Continue all standard screening.
You'll be referred for directed imaging based on the predicted cancer signal origin. Most positive results are followed up within 4-8 weeks. Workup may confirm a cancer (allowing earlier intervention) or identify a non-cancer cause of the signal.
The intended use is annual screening, similar to other annual tests. Whether this is right for you depends on age, family history, and other factors.
Galleri is currently studied and recommended primarily for adults 50+. Younger adults with strong family history may be candidates — discuss with your clinician.
10-14 business days from the blood draw.
Book online and a licensed clinician orders the test for you, so no separate doctor's visit is needed. You then complete a standard blood draw arranged after your order.
The Galleri test is listed on request. Pricing is self-pay, so you don't need insurance, and your clinician review is included.
You complete a standard blood draw arranged after your order. Your order confirmation explains exactly what to do and when.
Your instructions tell you whether fasting or any other preparation is needed. Blood panels that include glucose and lipids usually require an 8 to 12 hour fast.
Timing depends on the test. You're notified as soon as results are ready, and a licensed clinician reviews them with you.
A licensed clinician reviews every result, explains what it means in plain language, and recommends next steps, including treatment if appropriate.
Yes. Your results are stored on a HIPAA-compliant platform and shared only with you and your care team.
Book a free consultation. Honest about what MCED testing can and can't do. Real clinical support throughout.