How Long Does Compounded Semaglutide Last in the Fridge?

Semaglutide compounded is a popular choice of those seeking to receive an individualized weight loss or type 2 diabetes treatment plan. Compounded semaglutide is similar to branded versions (Wegovy and Ozempic), however, the patient composed semaglutide is often formulated by compounding pharmacies to meet the unique needs of patients. A common question among users is: for how long does compounded semaglutide last in the fridge?
Medications should only be stored properly to stay effective and safe. This article investigates the shelf life of compounded semaglutide, storage guideline, and suggestions for how long you can expect it to be effective.

Compounded Semaglutide – What You Need to Know

Semaglutide compounded is the custom prepared version of the drug tailored for each individual’s personal needs. Semaglutide is compounded into this formulation by compounding pharmacies, which means they combine semaglutide with other ingredients to help the patient either get the dose they need or want it administered in a different way. The preparation and stability of the medication may vary from that for commercially available versions, the active ingredient remaining the same.
Compounded medications need a number of items, including: storage instructions, such as refrigeration, as to not lose stability wherein it differs from the branded product.

Reasons Why Refrigeration is Required for Semaglutide

Semaglutide is a peptide based medication, meaning it is temperature and light sensitive as well as somewhat humidity sensitive. Storage of the active compound incorrectly can degrade the active compound so it is no longer effective, or even dangerous.

Temperature Sensitivity:

Storage semaglutide must be stored in cool environment. The medication can break-down when exposed to heat.

Refrigeration Guidelines:

At temperatures of 36 degrees to 46 degrees Fahrenheit (2 to 8 degrees Celsius), the range typical of household refrigerators, compounded semaglutide should be stored.

How Long Does Compounded Semaglutide Stay Fresh in the ‘Fridge’?

The shelf life of compounded semaglutide in the fridge varies according to preparation techniques, ingredients added and storage conditions. In general:

Typical Shelf Life:

When stored properly, most of the compounded semaglutide formulations are good for 1 to 30 to 90 days in the fridge. Yet the precise period needs to be stated on the label or made by the pharmacist.

Expiration Date:

Never rely on receiving this product from the compounding pharmacy without checking the expiration date given. Stability does not mean the expiration date, but the expiration date applies only to the specific formulation.

Opened vs. Unopened Vials:

Unopened Vials: Semaglutide compounded typically remains fully potent for the time specified by the pharmacy.

Opened Vials: If medication is once opened, the shelf life may become shorter. Opened vials should be used within 4–6 weeks, even if kept in the fridge, many pharmacies recommend.

Freezing:
The semaglutide in prefilled pens is designed to be audible and visible and is intended not to be frozen.

Indications that Compounded Semaglutide May Expired

If you used expired or improperly stored semaglutide, it won’t be as effective or safe. Watch for the following signs that the medication may no longer be viable:
Discoloration: This is a solution which is cloudy, yellow, or containing visible particles.
Changes in Texture: Degraded products may have a gel like consistency or clumping.
Unusual Odor: Spoiled may mean flavored with foul or unusual smell.
Reduced Effectiveness: A loss of potency may be indicated by lack of expected results.
Stop use and ask a healthcare provider or pharmacist if you observe any of the following signs.

Tips for Storing Semaglutide Compounded

To ensure the longevity and effectiveness of compounded semaglutide, follow these storage tips:
Set the Right Temperature:
Between 36°F and 46°F (2°C to 8°C), store the medication in the fridge. Don’t refrigerate in the door, as it could be exposed to temperature swings.
Keep It Sealed:
Do not keep semaglutide without using the right vial or container with the lid properly closed.
Protect from Light:
Semaglutide can be degraded by exposure to light. Keep the vial in opaque container in the fridge.
Monitor Expiration Dates:
Always look through the label and take the medication within the right period of time.
Avoid Freezing:
Never freeze semaglutide because once frozen, the medication’s molecular structure is damaged.
Transport Safely:
Semaglutide is to be transported by a cooler with ice packs, during which temperature range shall be maintained.

What to Do If the Fridge Forms a Nail Hole in Semaglutide

Compounded semaglutide can be accidentally left out of the fridge. How exposed and the ambient temperature determine how long the medication can be stable at room temperature.

Short Periods (Less Than 24 Hours):
The good news is that if semaglutide has been at room temp for less than 24 hours and it’s been kept below 77°F (25°C), it’s likely still safe to use. If you can, return it to the fridge ASAP.

Extended Periods (More Than 24 Hours):
While not all drugs are heat sensitive, if your medication has been unrefrigerated for more than 24 hours or at a temperature higher than 77°F, the medication can now be unsafe. To contact a pharmacist or healthcare provider.

What is the best way to be most effective with Semaglutide?

In addition to proper storage, consider the following practices to maximize the benefits of compounded semaglutide:
Follow Dosage Instructions:
Follow the instructions about when to take medication exactly as you are advised. Missed doses will affect its effectiveness.
Work with a Trusted Pharmacy:
Make sure that your compounds semaglutide are prepared with a reputable pharmacy according to strict quality standards.
Maintain Consistent Storage:
After all, we can frequently find ourselves away from home during travel or vacations, so using portable coolers to store semaglutide in the fridge is necessary at all times.
Dispose of Expired Medication:
Throw away semaglutide that’s expired or spent time at room temperature. Use your pharmacy or other disposal methods approved by your pharmacist.

Consulting Your Pharmacist

Consult your compounding pharmacist regarding shelf life or storage of your compounded semaglutide for specific questions. This allows them to offer you tailored advice that takes into account that formulation of your prescription.

Semaglutide: Effective Dosing and Guidance with HealifyNow

At HealifyNow, we provide expert insights and support to help you make the most of your semaglutide-based weight management journey. Semaglutide, a groundbreaking GLP-1 receptor agonist, is available in both subcutaneous injections and oral tablets, offering flexibility for individuals looking to combat obesity and related health concerns.

Conclusion

Just like injected semaglutide, compounded semaglutide should last 30 to 90 days when properly stored in the fridge. Medication kept between 36°F and 46°F (2°C to 8°C) keeps its potency and safety in order. In case you receive any medication from your pharmacy make sure you always check the expiration date and follow the storage guidelines carefully.Following these best practices can help guarantee the success of your compounded semaglutide and ultimately grant you your treatment goals, all while doing so safely and effectively.

Jessie Platt